Heart Disease Clinical Trials

Stem Cell Mobilization to Treat Chest Pain and Shortness of Breath in Patients With Coronary Artery Disease – http://clinicaltrial.gov/ct2/show/NCT00043628?term=stem+cell+heart&rank=4

Myocardial Regeneration and Angiogenesis in Myocardial Infarction With G-CSF and Intra-Coronary Stem Cell Infusion-3-DES – http://clinicaltrial.gov/ct2/show/NCT00291629?term=stem+cell+heart&rank=32

Stem Cell Therapy for Vasculogenesis in Patients With Severe Myocardial Ischemia – http://clinicaltrial.gov/ct2/show/NCT00260338?term=stem+cell+heart&rank=35

Bone Marrow Stem Cell Mobilization Therapy for Acute Myocardial Infarction (AMI)(REVIVAL-2) – http://clinicaltrial.gov/ct2/show/NCT00126100?term=stem+cell+heart&phase=3&rank=8

The Effect of Mobilized Stem Cell by G-CSF and VEGF Gene Therapy in Patients With Stable Severe Angina Pectoris – http://clinicaltrial.gov/ct2/show/NCT00135850?term=stem+cell+heart&rank=43

Endothelial Progenitor Cells and Nitric Oxide in Cardiac Rehabilitation Program Participants – http://clinicaltrial.gov/ct2/show/NCT00308633?term=stem+cell+heart&rank=50

One of the RSCI favorites…

Stem Cell Study for Patients With Heart Disease – http://clinicaltrial.gov/ct2/show/NCT00081913?term=stem+cell+heart&rank=58

METHODS AND RESULTS: Twenty-four patients (19 men and 5 women aged 48 to 84 years) with Canadian Cardiovascular Society class 3 or 4 angina who were undergoing optimal medical treatment and who were not candidates for mechanical revascularization were enrolled in a double-blind, randomized (3:1), placebo-controlled dose-escalating study.

CONCLUSION: A randomized trial of intramyocardial injection of autologous CD34+ cells in patients with intractable angina was completed that provides evidence for feasibility, safety, and bioactivity.